Table of Contents

  1. Physical Supplement Facts Table
  2. The 9 Active Ingredients Evaluated
  3. Three Formulation Elements We Discount, and Why
  4. Medication Interactions Worth Clearing First
  5. Summary & Ordering Recommendation

The Official Supplement Facts Table

Unlike promotional websites that hide dosage details, this reference ledger transcribes the exact Supplement Facts panel from the physical packaging of NeuroRecall. Each bottle contains 30 vegetable capsules, intended for a daily serving of 1 capsule taken with an 8 oz. glass of water.

Active Ingredient Chemical Form / Source Amount Per Serving % Daily Value
Thiamin Thiamine Hydrochloride 6 mg 500%
Vitamin B6 Pyridoxine Hydrochloride 8.5 mg 500%
Vitamin B12 Methylcobalamin (Bioactive) 24 mcg 1000%
Proprietary Blend 151 mg *
Caffeine from Green Coffee Coffea arabica bean extract Undisclosed fraction of 151 mg *
L-Tyrosine Free-form amino acid Undisclosed fraction of 151 mg *
Bacopa Extract Bacopa monnieri (std. 20% Bacosides) Undisclosed fraction of 151 mg *
Theacrine 1,3,7,9-tetramethyluric acid Undisclosed fraction of 151 mg *
Theobromine 3,7-dimethylxanthine Undisclosed fraction of 151 mg *
Rhodiola Extract Rhodiola rosea root extract Undisclosed fraction of 151 mg *

* Daily Value not established. Other Ingredients: Rice Flour, Hypromellose (vegetable capsule), Magnesium Stearate, Silicon Dioxide.

Detailed Analysis of the 9 Active Components

Below is our clinical evaluation of each individual active ingredient against published peer-reviewed human trials indexed in PubMed and the National Library of Medicine.

ACTIVE 01 90% Clinical Backing

Thiamin (as thiamine hydrochloride)

Thiamine HCl (Vitamin B1)
Dose: 6 mg (500% DV) · Disclosed on Physical Label

Thiamine is an essential enzymatic co-factor for pyruvate dehydrogenase and alpha-ketoglutarate dehydrogenase in the neuronal citric acid cycle. The human central nervous system consumes approximately 20% of whole-body glucose despite representing only 2% of total body mass. Clinical human trials establish that adequate thiamine status is non-negotiable for neuronal energy synthesis, myelin stability, and the presynaptic generation of acetylcholine, the primary neurotransmitter governing working memory and rapid information encoding (Gibson et al. 2013).

Clinical Verdict: Fully disclosed at 6 mg (500% Daily Value); proven biochemical role in neuronal glucose metabolism and acetylcholine neurotransmission.
ACTIVE 02 88% Clinical Backing

Vitamin B6 (as pyridoxine hydrochloride)

Pyridoxine HCl (Vitamin B6)
Dose: 8.5 mg (500% DV) · Disclosed on Physical Label

Vitamin B6 serves as an indispensable coenzyme in its active pyridoxal 5'-phosphate (PLP) form for aromatic L-amino acid decarboxylase. This rate-limiting enzymatic reaction biosynthesizes dopamine, serotonin, and GABA from dietary amino acids. Furthermore, vitamin B6 acts in the cystathionine beta-synthase pathway to break down homocysteine—an inflammatory vascular byproduct that damages delicate cerebral capillaries and accelerates brain parenchymal atrophy when elevated (Smith et al. 2010).

Clinical Verdict: Fully disclosed at 8.5 mg (500% Daily Value); mandatory enzymatic co-factor for neurotransmitter synthesis and homocysteine clearance.
ACTIVE 03 92% Clinical Backing

Vitamin B12 (as methylcobalamin)

Bioactive Methylcobalamin
Dose: 24 mcg (1000% DV) · Disclosed on Physical Label

NeuroRecall utilizes methylcobalamin, the pre-methylated, physiologically active coenzyme form of cobalamin, rather than synthetic cyanocobalamin. Methylcobalamin donates methyl groups directly to the remethylation of homocysteine to methionine, facilitating S-adenosylmethionine (SAMe) production and safeguarding the fatty myelin sheaths that insulate cerebral axon terminals. Published clinical investigations demonstrate that methylated B12 optimizes nerve conduction velocity and protects against age-accelerated executive decline (O'Leary et al. 2012).

Clinical Verdict: Fully disclosed at 24 mcg (1000% Daily Value); superior methylated coenzyme supporting axonal myelin maintenance and cognitive longevity.
ACTIVE 04 91% Clinical Backing

Caffeine from Green Coffee (Coffea arabica) Bean Extract

Natural Unroasted Green Coffee Bean Extract
Dose: Proprietary Blend (undisclosed fraction of 151 mg) · Masked Inside 151 mg Proprietary Blend

Natural caffeine extracted from green coffee beans acts as a competitive antagonist at central adenosine A1 and A2A receptors, preventing somnogenic adenosine binding and maintaining neuronal firing rates. Unlike anhydrous synthetic caffeine, unroasted green coffee bean extract carries naturally occurring chlorogenic acids that buffer caffeine uptake, promoting sustained alertness, psychomotor speed, and reaction vigilance while reducing the likelihood of abrupt sympathetic nervous spikes (McLellan et al. 2016, Haskell-Ramsay et al. 2018).

Clinical Verdict: Extensive clinical literature backing immediate alertness, attention vigilance, and reaction speed; exact milligram amount masked in the 151 mg blend.
ACTIVE 05 82% Clinical Backing

L-Tyrosine

Free-Form Amino Acid Precursor
Dose: Proprietary Blend (undisclosed fraction of 151 mg) · Masked Inside 151 mg Proprietary Blend

L-Tyrosine is the direct precursor amino acid for dopamine, norepinephrine, and epinephrine synthesis. Under sustained cognitive demand, emotional stress, or sleep fragmentation, central catecholamine stores become depleted, manifesting as mental fatigue and executive dysfunction. Human clinical trials (Deijen et al. 1999, Banderet et al. 1989) show that supplemental L-tyrosine selectively replenishes depleted catecholamines, preserving working memory and mental flexibility under acute cognitive stress.

Clinical Verdict: Established physiological support for neurotransmitter replenishment under cognitive stress; standalone studies test 500–2,000 mg, exceeding the entire 151 mg blend.
ACTIVE 06 89% Clinical Backing

Bacopa (Bacopa monnieri) Whole Plant Extract

Standardized Whole Plant Extract (std. to 20% Bacosides)
Dose: Proprietary Blend (undisclosed fraction of 151 mg) · Masked Inside 151 mg Proprietary Blend

Bacopa monnieri is an Ayurvedic botanical nootropic evaluated in rigorous double-blind, placebo-controlled human randomized controlled trials (Stough et al. 2001, Calabrese et al. 2008, Morgan et al. 2010). Its active triterpenoid saponins (bacosides A and B) enhance synaptic transmission, protect hippocampal neurons from lipid peroxidation, and stimulate dendritic branching. Clinical outcomes demonstrate statistically significant improvements in higher-order information processing, visual information recall, and verbal learning after 8 to 12 weeks of daily administration.

Clinical Verdict: High-tier RCT human evidence for delayed recall and memory consolidation; standardized to 20% bacosides, but the full 300 mg clinical dose cannot fit within a 151 mg total blend.
ACTIVE 07 79% Clinical Backing

Theacrine

Pure Purine Alkaloid (1,3,7,9-tetramethyluric acid)
Dose: Proprietary Blend (undisclosed fraction of 151 mg) · Masked Inside 151 mg Proprietary Blend

Theacrine is a purine alkaloid structurally related to caffeine discovered in Kucha tea (Camellia kucha). Pharmacological trials demonstrate that theacrine modulates both adenosine and dopamine receptors without causing receptor downregulation, meaning it provides sustained mental clarity, energetic drive, and cognitive stamina with substantially less habituation, tolerance development, or cardiovascular heart rate spikes than pure caffeine (Ziegenfuss et al. 2016, Habowski et al. 2014).

Clinical Verdict: Solid clinical pharmacology demonstrating sustained non-habituating alertness; synergizes smoothly with green coffee caffeine, though exact milligrams remain undisclosed.
ACTIVE 08 76% Clinical Backing

Theobromine

Cacao Xanthine Alkaloid (3,7-dimethylxanthine)
Dose: Proprietary Blend (undisclosed fraction of 151 mg) · Masked Inside 151 mg Proprietary Blend

Theobromine is a natural dimethylxanthine alkaloid predominantly derived from cacao. While displaying weaker central adenosine antagonism than caffeine, it exerts prominent phosphodiesterase-inhibiting and smooth-muscle relaxing effects. This promotes peripheral and cerebral microvascular vasodilation, increasing blood flow velocity and oxygen delivery to cortical capillary beds without driving sudden spikes in systemic arterial pressure (Baggott et al. 2013, Mitchell et al. 2011).

Clinical Verdict: Clinically supported for cerebral blood flow and smooth stimulant modulation; exact milligram fraction within the 151 mg blend is hidden.
ACTIVE 09 85% Clinical Backing

Rhodiola (Rhodiola rosea) Root Extract

Arctic Root Adaptogen Extract (Rosavins & Salidroside)
Dose: Proprietary Blend (undisclosed fraction of 151 mg) · Masked Inside 151 mg Proprietary Blend

Rhodiola rosea is a high-altitude adaptogenic root botanical evaluated across multiple double-blind clinical trials (Darbinyan et al. 2000, Spasov et al. 2000, Olsson et al. 2009). Its active rosavins and salidrosides modulate the hypothalamic-pituitary-adrenal (HPA) axis, attenuating cortisol release and preventing stress-induced depletion of cerebral ATP and neuropeptide Y. Clinical human studies verify marked reductions in intellectual fatigue, enhanced attention endurance during complex tasks, and stabilization of daytime mood.

Clinical Verdict: Robust clinical evidence for stress fatigue resistance and mental endurance; standalone studies employ 100–300 mg, indicating NeuroRecall relies on a micro-dosed botanical complex.

Three Formulation Elements We Discount, and Why

An honest clinical reference ledger must point out weaknesses as well as strengths. In evaluating NeuroRecall, our toxicological and nutritional review identifies three clear limitations:

1. The 151 mg Proprietary Blend Masks Individual Botanicals

By grouping Green Coffee Caffeine, L-Tyrosine, Bacopa, Theacrine, Theobromine, and Rhodiola into a single 151 mg proprietary blend, the manufacturer legally withholds the exact milligram weight of each compound. Consumers cannot determine whether Bacopa provides 20 mg or 80 mg, nor can they verify the exact caffeine level.

2. Botanical Amounts Fall Below Standalone Clinical Megadoses

Human double-blind trials demonstrating enhanced memory acquisition typically test Bacopa monnieri at 300 mg daily, Rhodiola rosea at 100–300 mg, and L-tyrosine at 500–2000 mg. Because the entire proprietary blend totals 151 mg, these compounds cannot possibly match the standalone dosages used in isolated human trials. NeuroRecall relies instead on micro-dose botanical synergy.

3. Perceived Immediate Alertness Relies on Xanthine Stimulants

Users frequently feel sharper within 45 minutes of ingestion. While marketing materials attribute this to cellular rejuvenation, pharmacology indicates this initial effect stems primarily from Green Coffee Caffeine and Theacrine antagonizing central adenosine receptors.

Medication Interactions Worth Clearing First

Because NeuroRecall contains active methylxanthines, amino acids, and methylated vitamins, several medical precautions must be observed:

  • Caffeine Sensitivity: Green coffee extract provides natural caffeine. Individuals who experience palpitations, tremors, or insomnia should avoid consuming additional coffee alongside this supplement.
  • Blood Pressure Medications: Theobromine and xanthines induce mild peripheral vasodilation and cardiac stimulation; individuals on antihypertensive therapy should monitor blood pressure.
  • MAO Inhibitors & Antidepressants: Free-form L-tyrosine is a catecholamine precursor. Combining high-dose tyrosine with MAOIs can provoke dangerous hypertensive crises.
  • Pregnancy & Nursing: Not recommended for pregnant or lactating women due to lack of safety data on theacrine and concentrated botanical extracts in developing fetuses.

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